師資
個人簡介：
醫(yī)學院講席教授。先后在第三軍醫(yī)大學燒傷研究所和創(chuàng)傷燒傷與復合傷國家重點實驗室從事燒傷和創(chuàng)面修復臨床治療與轉化研究，主要研究微環(huán)境與創(chuàng)面修復，以及微環(huán)境營造促進創(chuàng)面原位修復再生的新技術和新材料的轉化，在國際和國內期刊發(fā)表論文350余篇，牽頭制定20余項全國臨床專家共識指南，發(fā)明專利7件，主、參編專著35部，獲國家科技進步二等獎4項等各級科技成果獎10余項，嚴重燒傷早期損害的救治技術被國家衛(wèi)生部列為適宜衛(wèi)生技術推廣項目, 發(fā)明的施加方向性電場創(chuàng)面敷料已申請創(chuàng)新醫(yī)療器械注冊。 先后擔任中華醫(yī)學會燒傷外科分會主任委員、中華燒傷雜志總編輯、《Burns》雜志高級編委、中國老年醫(yī)學學會燒創(chuàng)傷分會會長、中國生物材料學會燒創(chuàng)傷創(chuàng)面修復材料分會主任委員、國家衛(wèi)生健康委能力建設和繼續(xù)教育創(chuàng)面修復科專家委員會副主任委員，參與國家自然科學基金學科評審和國家科技進步獎評審。培養(yǎng)碩士和博士研究生70余名。
為國家杰出青年科學基金獲得者，首屆新世紀百千萬人才工程國家級人選，全國優(yōu)秀科技工作者，獲中國醫(yī)師獎、燒傷醫(yī)學終身成就獎。
教育背景：
1978.09-1983.07 第三軍醫(yī)大學軍醫(yī)系學員，獲醫(yī)學學士學位
1983.08-1986.07 第三軍醫(yī)大學燒傷外科學碩士研究生，獲醫(yī)學碩士學位
1986.08-1989.11 第三軍醫(yī)大學燒傷外科學博士研究生，獲醫(yī)學博士學位
工作經歷：
1989.12-1997.04 第三軍醫(yī)大學燒傷研究所主治醫(yī)師，講師，副主任醫(yī)師，副教授，主任醫(yī)師，教授，博士導師，副所長
1997.05-1999.06 美國德克薩斯大學加爾維斯頓醫(yī)學分校 博士后
1999.07-1999.11 第三軍醫(yī)大學燒傷研究所副所長，主任醫(yī)師，教授，博士導師
1999.12-2010.08 第三軍醫(yī)大學燒傷研究所所長，主任醫(yī)師，教授，博士導師
2003.03-2005.05 創(chuàng)傷、燒傷與復合傷國家重點實驗室副主任 博士導師，主任醫(yī)師，教授，
2005.06-2017.07 創(chuàng)傷、燒傷與復合傷國家重點實驗室主任，主任醫(yī)師，教授， 博士導師
2006.06-2010.08 第三軍醫(yī)大學西南燒傷?？漆t(yī)院院長
2010.08-2022.05 第三軍醫(yī)大學燒傷研究所名譽所長，主任醫(yī)師，教授，博士導師
2017.07-2022.05創(chuàng)傷、燒傷與復合傷國家重點實驗室主任顧問，主任醫(yī)師，教授，博士導師
2022.05- 南方科技大學醫(yī)學院創(chuàng)面修復與再生醫(yī)學研究所 講席教授
2022.05- 南方科技大學醫(yī)院創(chuàng)面修復科 主任醫(yī)師、教授，科主任
獲獎情況及榮譽：
獲國家科技進步二等獎4項（第一完成人2項）、省部級科技進步一等獎3項，黎鰲燒傷醫(yī)學獎一等獎1項。
首批新世紀百千萬人才工程國家級人選、全國優(yōu)秀科技工作者、中國醫(yī)師獎、中國科協(xié)求是杰出青年實用工程獎、燒傷醫(yī)學終身成就獎、國家有突出貢獻中青年專家、全軍杰出專業(yè)技術人才、重慶市杰出專業(yè)技術人才、重慶市首席醫(yī)學專家等。
研究領域：
創(chuàng)面微環(huán)境與修復，營造促進創(chuàng)面原位修復再生的新技術和新材料研發(fā)與臨床評價，以及創(chuàng)面修復臨床技術。
學術任職：
中華醫(yī)學會理事會（第23-25屆）理事、中華醫(yī)學會燒傷外科學分會（第七屆）主任委員、中華燒傷雜志第三和第四屆總編輯、中國老年醫(yī)學學會燒創(chuàng)傷分會會長、中國生物材料學會燒創(chuàng)傷創(chuàng)面臨床應用分會主任委員、中國研究型醫(yī)院學會生物材料臨床應用專業(yè)委員會主任委員、國家衛(wèi)生健康委能力建設和繼續(xù)教育創(chuàng)面修復科專家委員會副主任委員、全軍第七和第八屆燒傷與整形外科專業(yè)委員會主任委員、第四軍醫(yī)大學軍事口腔醫(yī)學國家重點實驗室學術委員會委員、第三軍醫(yī)大學創(chuàng)傷燒傷與復合傷國家重點實驗室學術委員會委員、暨南大學再生醫(yī)學教育部重點實驗室學術委員會委員、海南醫(yī)科大學教育部重點實驗室學術委員會委員，以及多個雜志副主編和編委等。
發(fā)表論文（部分）：
1 Yan Shi,Shang Wang, Ronghua Yang, Zhenmin Wang, Weiwei Zhang, Hongwei Liu#, and Yuesheng Huang#. ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/-Catenin. Oxidative Medicine and Cellular Longevity, 2022, Article ID 1084006.
2 Yan-hai Feng, Ling-fei Li, Qiong Zhang, Jun-hui Zhang, Yao Huang, Yan-ling Lv, Jie-Zhi Jia, Dongxia Zhang, Jiong-Yu Hu# and Yue-Sheng Huang#. Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related Pyroptosis. Cell Death Discovery, 2021, 7:213.
3 Yao Huang, Yanhai Feng, Lin Cui, Lei Yang, Qiong Zhang, Junhui Zhang,Xupin Jiang, Xingyue Zhang, Yanling Lv, Jie-Zhi Jia, Dong-Xia Zhang#，Yue-Sheng Huang#. Autophagy-Related LC3 Accumulation nteracted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes. Front. Cell Dev. Biol. , 2021, 9: 679637.
4 Wei Jinyu, Lin Jiezhi, Zhang Junhui, Tang Di, Xiang Fei, Cui Lin, Zhang Qiong, Yuan Hongping, Song Huapei, Lv Yanling, Jia Jiezhi, Zhang Dongxia #, Huang Yuesheng#, TRPV1 Activation Mitigates Hypoxic Injury in Mouse Cardiomyocytes by Inducing Autophagy Through the AMPK Signaling Pathway. Am J Physiol Cell Physiol. 2020; 318(5):C1018-C1029.
5 Yi Liang, Hao Tian, Jie Liu , YanLing Lv, Yuan Wang, JiaPing Zhang#, YueSheng Huang#. Application of stable continuous external electric field promotes wound healing in pig wound model. Bioelectrochemistry, 2020, 135: 107578.
6 Xiaodong Lan, Zhiyong Huang, Ziming Tan, Zhenjia Huang, Dehuai Wang#，Yuesheng Huang#. Nebulized heparin for inhalation injury in burn patients: a systematic review and meta-analysis. Burns & Trauma, 2020, 8: tkaa015
7 Zhang X, Li L, Zhang Q, Wei Q, Lin J, Jia J, Zhang J, Yan T, Lv Y, Jiang X, Zhang P, Song H, Zhang D#，Huang Y# . CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions. Front. Cell Dev. Biol. , 2020, 8: 191.
8 Lin Cui, Li-Ping Zhao, Jing-Ying Ye, Lei Yang, Yao Huang, Xu-Pin Jiang, Qiong Zhang, Jie-Zhi Jia, Dong-Xia Zhang#, Yuesheng Huang#. The Lysosomal Membrane Protein Lamp2 Alleviates Lysosomal Cell Death by Promoting Autophagic Flux in Ischemic Cardiomyocytes. Front. Cell Dev. Biol., 2020, 8: 31.
9 Xupin Jiang, Miao Teng, Ran Ji, Dongxia Zhang, Ze Zhang, Yanling Lv, Qiong Zhang, Jiaping Zhang#, Yuesheng Huang#. CD9 regulates keratinocyte differentiation and motility by recruiting Ecadherinto the plasma membrane and activating the PI3K/Akt pathway. BBA - Molecular Cell Research 2020; 1867 :118574
10 Junhui Zhang, Can Zhang, Xupin Jiang, Lingfei Li, Dongxia Zhang, Di Tang, Tiantian Yan, Qiong Zhang,Hongping Yuan, Jiezhi Jia, Jiongyu Hu, Jiaping Zhang，Yuesheng Huang*. Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration. Cell Death and Disease 2019；10:234.
11 Tiantian Yan, Xupin Jiang, Guoan Lin, Di Tang, Junhui Zhang, Xiaowei Guo, Dongxia Zhang, Qiong Zhang, Jiezhi Jia, Yuesheng Huang*. Autophagy is required for the directed motility of keratinocyte driven by electric fields. FASEB J . 2019; 33(3): 3922-3935.
12 Lei Yang, Liping Zhao, Lin Cui, Yao Huang, Jingying Ye, Qiong Zhang, Xupin Jiang, Dongxia Zhang#, Yuesheng Huang#. Decreased α-tubulin acetylation induced by an acidic environment impairs autophagosome formation and leads to rat cardiomyocyte injury. J Mol Cell Cardiol. 2019; 127: 143-153.
13 Lingfei Li, Xingyue Zhang, Qiong Zhang, Jiezhi Jia,Junhui Zhang,Dongxia Zhang, Huapei Song, Bing Chen , Jiongyu Hu# , Yuesheng Huang#. Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.Oxidative Medicine and Cellular Longevity 2019；Article ID 6428924.
14 Junhui Zhang, Lingfei Li, Qiong Zhang, Xu Yang, Can Zhang, Xingyue Zhang, Dongxia Zhang, Yanling Lv, Huapei Song, Bing Chen, Yao Liu, Jiongyu Hu#, Yuesheng Huang#. Phosphorylation of Microtubule-Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation. Front. Pharmacol. 2019;10:368.
15 Li L, Zhang J, Zhang Q, Zhang D, Xiang F, Jia J, Wei P, Zhang J, Hu J#， Huang Y#. High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway. Front. Physiol. 2019;10:24.
16 Lingfei Li, Junhui Zhang, Qiong Zhang, Yuesheng Huang#. Jiongyu Hu#. Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction. Burns & Trauma 2019; 7:8.
17 Fei Xiang, Si-yuan Ma, Yan-ling Lv, Dong-xia Zhang, Hua-pei Song，Yue-sheng Huang*.Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II. Burns& Trauma 2019; 7:16.
18 Junhui Zhang, Lingfei Li, Qiong Zhang, Wensheng Wang, Dongxia Zhang, Jiezhi Jia, Yanling Lv, Hongping Yuan, Huapei Song, Fei Xiang, Jiongyu Hu#, Yuesheng Huang#. Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation. Int J Biol Sci.，2019; 15(9): 1962-1976.
19 Lingfei Li, Qiong Zhang, Xingyue Zhang, Junhui Zhang, Xuefeng Wang, Jun Ren, Jiezhi Jia, Dongxia Zhang, Xupin Jiang, Jiaping Zhang, Hao Mei, Bing Chen, Jiongyu Hu#, Yuesheng Huang#. Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice. EBioMedicine 2018；37:221-235.
20 Hao Tian, Liangxi Wang, WeiguoXie, Chuanan Shen, Guanghua Guo, Jiaqi Liu, Chunmao Han, Licheng Ren, Yi Liang, Yong Tang, Yuan Wang, Weifang Yin, Jiaping Zhang# , Yuesheng Huang#. Epidemiologic and clinical characteristics of severe burn patients: results of a retrospective multicenter study in China, 2011-2015. Burns & Trauma 2018; 6(2): 140-150.
21 Junhui Zhang，Dongxia Zhang，Tiantan Yan，Xupin Jiang，Can Zhang，?Liping Zhao，Lingfei Li，Di Tang，Qiong Zhang，Jiezhi Jia，Jiaping Zhang，Yuesheng Huang #. BNIP3 promotes the motlity and migraton of keratnocyte under hypoxia. Experimental Dermatology 2017; 26: 416–422.
22 Di Tang, Tiantian Yan, Junhui Zhang, Xupin Jiang, Dongxia Zhang, Yuesheng Huang*. Notch1 Signaling Contributes to Hypoxia-induced High Expression of Integrin β1 in Keratinocyte Migration. Scientific Reports 2017; 7:43926.
23 Tiantian Yan, Junhui Zhang, Di Tang, Xingyue Zhang, Xupin Jiang, Liping Zhao, Qiong Zhang, Dongxia Zhang, Yuesheng Huang*. Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway. PLoS ONE， 2017; 12(1): e0169155.
24 Tiantian Yan, Xupin Jiang, Xiaowei Guo, Wen Chen, Di Tang, Junhui Zhang, Xingyue Zhang, Dongxia Zhang, Qiong Zhang, Jiezhi Jia, Yuesheng Huang*. Electric field-induced suppression of PTEN drives epithelial-to -mesenchymal transition via mTORC1 activation. J Dermatol Sci， 2017; 85(2): 96–105.
25 Chen Wen，Jiang Youzhao， Han Jian， Hu Jiongyu，He Ting， Yan Tiantian，Huang Na，Zhang Qiong，Mei Hao，Liao Yong，Huang Yuesheng#，Chen, Bing#. Atgl deficiency induces podocyte apoptosis and leads to glomerular filtration barrier damage. FEBS Journal, 2017; 284(7): 1070-1081.
26 Liping Zhao, Lin Cui, Xupin Jiang, Junhui Zhang, Minghua Zhu, Jiezhi Jia, Qiong Zhang, iaping Zhang, Dongxia Zhang#, Yuesheng Huang#. Extracellular pH regulates autophagy via the AMPK–ULK1 pathway in rat cardiomyocytes. FEBS Letters，2016；590 ：3202–3212 （IF 4.124）
27 Fei Xiang, Si-Yuan Ma, Dong-Xia Zhang, Qiong Zhang, Yue-Sheng Huang*. Tumor necrosis factor receptor-associated protein 1 improveshypoxia-impaired energy production in cardiomyocytes through increasing activity of cytochrome c oxidase subunit II. Int J Biochem Cell Biol , 2016；79：239–248.
28 Zhang Dong-Xia, Zhang Jia-Ping, Hu Jiong-Yu, Huang Yue-Sheng*. The potential regulatory roles of NAD+ and its metabolism in autophagy. Metabolism: Clinical and Experimental. 2016，65: 454–462.
29 Xiaodong Lan, Lingfei Li, Jiongyu Hu, Qiong Zhang, Yongming Dang#, Yuesheng Huang#. A Quantitative Method for Microtubule Analysis in Fluorescence Images. Microsc. Microanal，2015， 21（12）：1582–1590.
30 Xiaowei Guo, Xupin Jiang, Xi Ren, Huanbo Sun, Dongxia Zhang, Qiong Zhang, Jiaping Zhang# ,Yuesheng Huang#. The Galvanotactic Migration of Keratinocytes is Enhanced by Hypoxic Preconditioning. Scientific Reports 2015; 5:10289.
31 Yongming Dang, Xiaodong Lan, Qiong Zhang, Lingfei Li, Yuesheng Huang*. Analysis of Grayscale Characteristics in Images of Labeled Microtubules from Cultured Cardiac Myocytes. Microsc. Microanal.2015, 21, 334–342.
32 Xupin Jiang, Dongxia Zhang, Hengshu Zhang, Yuesheng Huang, Miao Teng. Role of Ran-regulated nuclear-cytoplasmic trafficking of pVHL in the regulation of microtubular stability-mediated HIF-1a in hypoxic cardiomyocytes. Sci Rep, 2015; 5 : 9193.
33 Lingfei Li, Jiongyu Hu, Ting He, Qiong Zhang, Xu Yang, Xiaodong Lan, Dongxia Zhang, Hao Mei, Bing Chen#, Yuesheng Huang#. P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury. Sci Rep 2015; 5 : 8895.
34 Ting He, Jiongyu Hu, Guangning Yan, Lingfei Li, Dongxia Zhang, Qiong Zhang, Bing Chen#, Yuesheng Huang#. Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis.Clin Sci 2015; 129: 49–61.
35 Xupin Jiang, Xiaowei Guo, Xue Xu, Miao Teng, Chong Huang, Dongxia Zhang, Qiong Zhang, Jiaping Zhang#, Yuesheng Huang#. Hypoxia regulates CD9-mediated keratinocyte migration xia the P38/MAPK pathway. Sci. Rep.,2014; 4, 6304.
36 J Hu , Z Chu , J Han , Q Zhang , D Zhang , Y Dang , J Ren , HC Chan , J Zhang#, Y Huang#. Phosphorylation-dependent mitochondrial translocation ofMAP4 is an early step in hypoxia-induced apoptosis in cardiomyocytes. Cell Death Dis, 2014, 5, e1424.
37 Xue Xu , Qiong Zhang , Jiong-yu Hu, Dong-xia Zhang, Xu-pin Jiang , jie-zhi Jia , Jing-ci Zhu#, Yue-sheng Huang#. Phosphorylation of DYNLT1 at Serine 82 Regulates MTs Stability and Mitochondrial Permeabilization in Hypoxia. Mol. Cells, 2013, 36（10）：322-332.
38 Dong-xia Zhang Hong Yan, Jiong-yu Hu, Jia-ping Zhang, Miao Teng, Da-li Tong, Fei Xiang, Qiong Zhang, Ya-dong Fang, Guang-ping Liang, Yue-sheng Huang*. Identification of mitochondria translation elongation factor Tu as a contributor to oxidative damage of postburn myocardium. J Proteomics, 2012; 77（9）：469-479.
39 Jiaping Zhang，Jianda Dong，Hua Gu，Sidney Yu，Xiaohu Zhang，Yulin Gou，Wenming Xu，Andrew Burd，Lin Huang，Kenji Miyado，Yuesheng Huang#, Hsiao Chang Chan#. CD9 Is Critical for Cutaneous Wound Healing through JNK Signaling. Journal of Investigative Dermatology 2012；132：226–236.
40 Miao Teng, XiaoHui Zhao, YueSheng Huang*. Regenerating cardiac cells: insights from the bench and the clinic. Cell Tissue Res 2012；350: 189–197.
41 Hong Yan, Dong-Xia Zhang, Xiaohua Shi, Qiong Zhang, Yue-sheng Huang*. Activation of the Prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytes. J Cell Mol Med. 2012；16（9）：2049-2059
42 Xiao Rong, Ze-Yuan Lei, MD, Yong-Ming Dang, Huang Yue-sheng*. Prompt Myocardial Damage Initiates Hepatic, Renal and Intestinal Injuries Early Following Severe Burns in Rats. J Trauma, 2011, 71: 663–672.
43 Jiong-Yu Hu, Zhi-Gang Chu, Jian Han, Hong Yan, Yong-ming Dang, Qiong Zhang, Yue-Sheng Huang*. p38/MAPK Pathway Regulates Microtubule Polymerization Through Phosphorylation of MAP4 and Op18 in hypoxic cells. Cell. Mol. Life Sci., 2010, 67(2):321–333.
44 Fei Xiang, Yue-Sheng Huang*, Xiao-Hua Shi and Qiong Zhang. Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening. FEBS J, 2010, 277 (8) ：1929–1938.
45 Miao Teng, Yong-Ming Dang, Jia-ping Zhang, Qiong Zhang, Ya-dong Fang, Jun Ren, Yue-sheng Huang*. Microtubular stability affects cardiomyocyte glycolysis by HIF-1α expression and endonuclear aggregation during early stages of hypoxia. Am J Physiol Heart Circ Physiol, 2010, 298（6）：H1919-H1931.
主編專著、參編教材：
1 黃躍生，呂國忠，姜玉峰，主編.國家衛(wèi)健委能力建設和繼續(xù)教育中心創(chuàng)面修復科?？颇芰ㄔO專用系列教材. 第三冊. 創(chuàng)面修復科全科醫(yī)師分冊. 鄭州：鄭州大學出版社，2021.
2 程飚，黃躍生，付小兵，主編。光、電及磁在創(chuàng)面治療中的應用.鄭州：鄭州大學出版社，2019.
3 黃躍生，主編。燒傷學名詞. 全國科學技術名詞審定委員會公布. 北京：科學出版社， 2019.
4 黃躍生，主編. 中華醫(yī)學百科全書.燒傷外科學。北京：中國協(xié)和醫(yī)科大學學出版社，2017.
5 黃躍生，粟永萍，周繼紅，主編. 特殊致傷原因戰(zhàn)創(chuàng)傷.鄭州：鄭州大學出版社，2016.
6 黃躍生，等主編. 燒傷關鍵治療技術及預防急救指南.北京：人民軍醫(yī)出版社，2015.
7 黃躍生，主編. 燒傷早期救治與康復治療學.石家莊：河北科學技術出版社，2015.
8 黃躍生，主編. 實用燒傷臨床治療學.鄭州:鄭州大學出版社,2013.
9 黃躍生，主編. 燒傷外科學。第1版。北京：科學技術文獻出版社，2010.
10 黃躍生，主編.燒傷科特色治療技術.北京：科學技術文獻出版社，2004.
11 黃躍生. 燒傷. 見：周總光，趙玉沛主編. 外科學（第2版）（高等學?！笆奈濉贬t(yī)學規(guī)劃新形態(tài)教材-供臨床、基礎、預防、護理、口腔、檢驗、藥學等專業(yè)用）. 北京：高等教育出版社， 2021.
12 黃躍生. 燒傷、凍傷. 見：陳孝平，汪建平，趙繼宗，主編. 外科學（第9版），（國家衛(wèi)健委“十三五”規(guī)劃教材，全國高等學校教材，供基礎、臨床、預防、口腔專業(yè)用）.北京：人民衛(wèi)生出版社，2018.
13 黃躍生.燒傷和冷傷. 見：陳孝平，主編. 外科學（全國高等醫(yī)藥院校8年制教材）.北京：人民衛(wèi)生出版社，2005.
14 黃躍生.燒傷與凍傷. 見：周總光，趙玉沛，主編.外科學（普通高等教育“十一五”國家級規(guī)劃教材，全國高等醫(yī)藥院校規(guī)劃教材）.北京：高等教育出版社，2009.
15 黃躍生.燒傷和凍傷. 見：陳孝平，主編.外科學（第2版）.全國高等學校教材供8年制及7年制臨床醫(yī)學等專業(yè)用. 北京：人民衛(wèi)生出版社，2010.
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