師資
苑秋月博士，南方科技大學(xué)助理教授，博士生導(dǎo)師。2016年本科畢業(yè)于北京師范大學(xué)數(shù)學(xué)與應(yīng)用數(shù)學(xué)專業(yè)，2021年獲得中國(guó)科學(xué)院數(shù)學(xué)與系統(tǒng)科學(xué)研究院運(yùn)籌學(xué)與控制論博士學(xué)位；隨后在美國(guó)克萊姆森大學(xué)人類遺傳學(xué)中心從事博士后研究，專注于在單細(xì)胞多組學(xué)上構(gòu)建基因調(diào)控網(wǎng)絡(luò)；2025年2月加入南方科技大學(xué)醫(yī)學(xué)院。研究結(jié)合了數(shù)學(xué)建模、人工智能和生物多組學(xué)數(shù)據(jù)，致力于揭示基因調(diào)控的動(dòng)態(tài)機(jī)制及其在精準(zhǔn)醫(yī)學(xué)中的應(yīng)用。迄今已發(fā)表多篇高質(zhì)量學(xué)術(shù)論文，包括以第一作者（含共同第一作者）身份在 Nature Biotechnology、Genome Biology、Nature Communications 等國(guó)際期刊的科研成果。
研究領(lǐng)域
1. 開發(fā)可解釋的人工智能模型，單細(xì)胞多組學(xué)數(shù)據(jù)解析基因調(diào)控網(wǎng)絡(luò)，推動(dòng)精準(zhǔn)醫(yī)學(xué)和個(gè)性化治療的發(fā)展。
2. 從調(diào)控的角度揭示細(xì)胞命運(yùn)決定的分子機(jī)制。
3. 結(jié)合優(yōu)化算法和機(jī)器學(xué)習(xí)，解決生物醫(yī)學(xué)中的復(fù)雜數(shù)據(jù)分析問(wèn)題。
教育背景
博士：運(yùn)籌學(xué)與控制論，中國(guó)科學(xué)院數(shù)學(xué)與系統(tǒng)科學(xué)研究院，2016年9月-2021年6月
本科：數(shù)學(xué)與應(yīng)用數(shù)學(xué)，北京師范大學(xué)，2012年9月-2016年7月
工作經(jīng)歷
博士后：克萊姆森大學(xué)人類遺傳學(xué)中心，2021年8月-2025年2月
助理教授：南方科技大學(xué)醫(yī)學(xué)院，2025年2月–至今
獲獎(jiǎng)情況及榮譽(yù)
2015年 國(guó)家獎(jiǎng)學(xué)金
2016年 北京市優(yōu)秀畢業(yè)生
2018年 首屆全球運(yùn)籌學(xué)挑戰(zhàn)賽季軍
2020年 中國(guó)科學(xué)院數(shù)學(xué)與系統(tǒng)科學(xué)研究院院長(zhǎng)獎(jiǎng)學(xué)金特別獎(jiǎng)
雜志編委會(huì)委員
擔(dān)任 Nature Communications，Gigascience，F(xiàn)rontiers in Genetics 等學(xué)術(shù)期刊的審稿人。
近年代表文章
*為共同第一作者
Yuan, Qiuyue, and Zhana Duren. "Inferring gene regulatory networks from single-cell multiome data using atlas-scale external data." Nature Biotechnology (2024): 1-11. https://www.nature.com/articles/s41587-024-02182-7
Yuan, Qiuyue, and Zhana Duren. "Integration of single-cell multi-omics data by regression analysis on unpaired observations." Genome Biology 23.1 (2022): 160. https://link.springer.com/article/10.1186/s13059-022-02726-7
Fei Li*, Qiuyue Yuan*, Wei Di, Xinyi Xia, Zhuang Liu, Ninghui Mao, Lin Li, Chunfeng Li, Juan He, Yunguang Li, Wangxin Guo, Xiaoyu Zhang, Yiqin Zhu, Rebiguli Aji, Shangqian Wang, Xinyuan Tong, Hongbin Ji, Ping Chi, Brett Carver, Yong Wang, Yu Chen, and Dong Gao. ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming[J]. Journal of Clinical Investigation, 2020. https://www.jci.org/articles/view/137967
Zhu, Yanjing*, Shijie Tang*, Qiuyue Yuan*, Jing Fu*, Juan He*, Zhuang Liu, Xiaofang Zhao et al. "Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions." Cell Reports Medicine 5, no. 2 (2024). https://www.cell.com/cell-reports-medicine/pdf/S2666-3791(23)00604-3.pdf
Xiaohan Shi*, Yunguang Li*, Qiuyue Yuan*, Shijie Tang*, Shiwei Guo*, Yehan Zhang, Juan He, Xiaoyu Zhang, Ming Han, Zhuang Liu, Yiqin Zhu, Suizhi Gao, Huan Wang, Xiongfei Xu, Kailian Zheng, Wei Jing, Luonan Chen, Yong Wang, Gang Jin & Dong Gao. "Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity." Nature Communications 13.1 (2022): 1-16. https://www.nature.com/articles/s41467-022-29857-6
Qiuyue Yuan, and Yong Wang. 3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model[J]. iScience, 2020, 23(6): 101227. https://www.sciencedirect.com/science/article/pii/S2589004220304120
Meng Zou, Zhana Duren, Qiuyue Yuan, Henry Li, Andrew Paul Hutchins, Wing Hung Wong, and Yong Wang. "MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting." Briefings in bioinformatics 22.6 (2021): bbab235. https://academic.oup.com/bib/article/22/6/bbab235/6309927?login=true
Guofeng Zhou, Shaoyan Sun, Qiuyue Yuan, Run Zhang, Ping Jiang, Guangyu Li, Yong Wang, and Xiao Li. "Multiple-Tissue and Multilevel Analysis on Differentially Expressed Genes and Differentially Correlated Gene Pairs for HFpEF." Frontiers in genetics 12 (2021). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296822/
Jingxue Xin*, Hui Zhang*, Yaoxi He*, Zhana Duren*, Caijuan Bai*, Lang Chen, Xin Luo, Dong-Sheng Yan, Chaoyu Zhang, Xiang Zhu, Qiuyue Yuan, Zhanying Feng, Chaoyiing Cui, Xuebin Qi, Ouzhuluobu NA, Wing Wong, Yong Wang, and Bing Su. Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation[J]. Nature communications, 2020, 11(1): 1-20. https://www.nature.com/articles/s41467-020-18638-8