個(gè)人簡(jiǎn)介：
崔歡歡，2016年博士畢業(yè)于柏林自由大學(xué)生物學(xué)專業(yè)，2018年12月加入南方科技大學(xué)，歷任研究助理教授、研究副教授，碩士生導(dǎo)師。主要研究方向?yàn)榛蜣D(zhuǎn)錄和表觀遺傳調(diào)控的機(jī)制研究和方法開發(fā)，RNA翻譯的順式調(diào)控元件和反式作用因子的鑒定與功能分析。
研究領(lǐng)域：
基因轉(zhuǎn)錄與表觀遺傳；
RNA翻譯調(diào)控。
工作經(jīng)歷：
2018.12 至今，南方科技大學(xué)；
2017.09– 2018.11，臨床科研經(jīng)理，深圳華大基因股份有限公司；
2016.05 – 2017.06，博士后，柏林夏洛蒂醫(yī)科大學(xué)；
2010.09 – 2011.08，柏林洪堡大學(xué)，研究助理。
學(xué)習(xí)經(jīng)歷：
2011.09 – 2016.04，柏林自由大學(xué)，生物學(xué)，博士；
2004.09 – 2010.06，西北農(nóng)林科技大學(xué)，國(guó)家生命科學(xué)基地班，本碩。
代表文章：
1. Cui H, Yi H, Bao H, Tan Y, Tian C, Shi X, Gan D, Zhang B, Liang W, Chen R, Zhu Q, Fang L, Gao X, Huang H, Tian R, Sperling SR, Hu Y, Chen W (2022) The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling. Nature Communications.
2. Yang C, Liu Y, Hu Y, Fang L, Huang Z, Cui H, Xie J, Hong Y, Chen W, Xiao N, Li Q, Liu W-H, Xiao C (2022) Myc inhibition tips the immune balance to promote antitumor immunity. Cellular & Molecular Immunology.
3. Tian S, Zhang B, He Y, Sun Z, Li J, Li Y, Yi H, Zhao Y, Zou X, Li Y, Cui H, Fang L, Gao X, Hu Y, Chen W (2022) CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference. Nucleic Acids Res.
4. Sun T, Zhang Z, Tian L, Zheng Y, Wu L, Guo Y, Li X, Li Y, Shen H, Lai Y, Liu J, Cui H, He S, Ren Y, Yang G (2022) Dualistic classification of high grade serous ovarian carcinoma has its root in spatial heterogeneity. J Adv Res.
5. Zhou J, Zhang B, Li H, Zhou L, Li Z, Long Y, Han W, Wang M, Cui H, Li J, Chen W, Gao X (2022) Annotating TSSs in Multiple Cell Types Based on DNA Sequence and RNA-seq Data via DeeReCT-TSS. Genomics Proteomics Bioinformatics.
6. Fang L, Li G, Sun Z, Zhu Q, Cui H, Li Y, Zhang J, Liang W, Wei W, Hu Y, Chen W (2021) CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing. Mol Syst Biol.
7. Yi H, Li G, Long Y, Liang W, Cui H, Zhang B, Tan Y, Li Y, Shen L, Deng D, Tang Y, Mao C, Tian S, Cai Y, Zhu Q, Hu Y, Chen W, Fang L (2020) Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT. Oncogene.
8. Fang L, Wang W, Li G, Zhang L, Li J, Gan D, Yang J, Tang Y, Ding Z, Zhang M, Zhang W, Deng D, Song Z, Zhu Q, Cui H, Hu Y, Chen W (2020) CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators. Mol Syst Biol.
9. Cui H, Schlesinger J, Schoenhals S, Tonjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR (2016) Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res.
10. Cui H, Bansal V, Grunert M, Malecova B, Dall'Agnese A, Latella L, Gatto S, Ryan T, Schulz K, Chen W, Dorn C, Puri PL, Sperling SR (2017) Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation. PLoS One.
11. Grunert M, Dorn C, Cui H, Dunkel I, Schulz K, Schoenhals S, Sun W, Berger F, Chen W, Sperling SR (2016) Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases. Cardiovasc Res.
12. Ben Jehuda R, Eisen B, Shemer Y, Mekies LN, Szantai A, Reiter I, Cui H, Guan K, Haron-Khun S, Freimark D, Sperling SR, Gherghiceanu M, Arad M, Binah O (2018) CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities. Heart Rhythm.
