師資
個人簡介
郭瓊玉，副教授，博士生導(dǎo)師。長期注重于高分子生物材料在轉(zhuǎn)化醫(yī)學(xué)方向的研發(fā)，將其應(yīng)用于多個具有挑戰(zhàn)性的生物醫(yī)學(xué)課題，在可移植人工角膜、介入栓塞材料、長效藥物控釋、記憶性納米材料以及細(xì)胞調(diào)控等領(lǐng)域里取得了突出的研究成果。郭瓊玉教授是深圳市海外高層次人才“孔雀計劃”B類獲得者，發(fā)表學(xué)術(shù)論文>40篇，被引用>1200次，申請專利15項，授權(quán)11項，其中可移植人工角膜和形狀記憶微納材料的研究成果在全球提交了多項專利申請，已經(jīng)獲得包括中國、美國、日本和歐洲等多個國家的專利授權(quán)；撰寫專著和章節(jié)2部；現(xiàn)任中國醫(yī)師協(xié)會介入醫(yī)師分會第三屆委員會介入醫(yī)學(xué)工程與生物技術(shù)學(xué)組委員、廣東省生物醫(yī)學(xué)工程學(xué)會智能介入醫(yī)學(xué)分會常務(wù)委員、深圳市生物醫(yī)學(xué)工程學(xué)會生物醫(yī)學(xué)材料專業(yè)委員會常委。
教育背景
2004年-2010年 美國凱斯西儲大學(xué)高分子工程 博士
1999年-2004年 中國科技大學(xué)高分子工程 學(xué)士
工作經(jīng)歷
2024年5月-至今 南方科技大學(xué)生物醫(yī)學(xué)工程系 副教授
2017年-2024年5月 南方科技大學(xué)生物醫(yī)學(xué)工程系 助理教授
2016年-2017年 美國里海大學(xué)生物工程 研究員
2009年-2016年 美國約翰霍普金斯大學(xué)生物醫(yī)學(xué)工程 博士后
獲獎及榮譽(yù)
2010-2013 美國關(guān)節(jié)炎基金博士后獎學(xué)金
研究興趣
郭瓊玉博士主要研究方向是開發(fā)納米至微米尺度新型形狀記憶性藥物釋放體系用于腫瘤治療和組織再生，其目標(biāo)為從材料、細(xì)胞、動物實驗多個層面為解決具體的臨床問題設(shè)計一系列智能材料。
代表論文
1. Q. Guo, D. Miller, H. An, H. Wang, J. Lopez, D. Lough, L. He and A. Kumar, “Controlled heat stress promotes myofibrillogenesis during myogenesis,” PLoS ONE 11(11) (2016) e0166294.
2. S. Majumdar, Q. Guo, M. Garza-Madrid, X. Calderon-Colon, D. Duan, P. Carbajal, O. Schein, M. Trexler, and J. Elisseeff, “Influence of collagen source on fibrillar architecture and properties of vitrified collagen membranes”, J. Biomed. Mater. Res. Part B. 104B (2016) 300-307.
3. Q Guo, J.P. Mather, P. Yang, M. Boden, and P.T. Mather, “Fabrication of polymeric coatings with controlled microtopographies using an electrospraying technique,” PLoS ONE 10(6) (2015) e0129960.
4. S. Yang,# Q. Guo,# L. Shores, A. Aly, M. Ramakrishnan, G.-H. Kim, Q. Lu, L. Su, G. Zhao, J.H. Elisseeff, “Use of a chondroitin sulfate bioadhesive to enhance integration of bioglass particles for repairing critical-size bone defects,” J. Biomed. Mater. Res. Part A. 103A (2015) 235-242. (#= Co-first author)
5. Q. Guo, J.M. Phillip, S. Majumdar, P. Wu, J. Chen, X. Calderón-Colón, O. Schein, B.J. Smith, M.M. Trexler, D. Wirtz, and J.H. Elisseeff, “Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair,” Biomaterials 34 (2013) 9365-9372.
6. Q. Guo,# X. Wang,# M.W. Tibbitt, K.S. Anseth, D.J. Montell, and J.H. Elisseeff, “Light activated cell migration in synthetic extracellular matrices,” Biomaterials 33 (2012) 8040-8046. (#= Co-first author)
7. Q. Guo, A. Aly, O. Schein, M.M. Trexler, and J.H. Elisseeff, “Moxifloxacin in situ gelling microparticles-bioadhesive delivery system,” Results in Pharma. Sciences 2 (2012) 66-71.
8. A.T. Hillel, S. Unterman, Z. Nahas, B. Reid, J.M. Coburn, J. Axelman, J.J. Chae, Q. Guo, R. Trow, A. Thomas, Z. Hou, S. Lichtsteiner, D. Sutton, C. Matheson, P. Walker, N. David, S. Mori, J.M. Taube, and J.H. Elisseeff, “Photoactivated composite biomaterial for soft tissue restoration in rodents and in human,” Sci. Tranl. Med. 3, 93ra67 (2011) 1-12.
9. Q. Guo, P.T. Knight, J. Wu, and P.T. Mather, “Blends of paclitaxel with POSS-based biodegradable polyurethanes: morphology, miscibility, and specific interactions,” Macromolecules 43 (2010) 4991-4999.
10. Q. Guo, P.T. Knight, and P.T. Mather, “Tailored drug release from biodegradable stent coatings based on hybrid polyurethanes,” J. Control. Release 137 (2009) 224-233.
著書章節(jié)
1. Q. Guo, and J.H. Elisseeff, Cartilage Tissue Engineering, in: A. Atala, R. Lanza, J.A. Thomson, R. Nerem (Eds.), Principles of Regenerative Medicine, 2nd Ed, Elsevier, 2011, pp. 981-995.
專利申請
1. Q. Guo, J. Green, R.A. Meyer, C.J. Bishop, A. Kumar, and G.L. Semenza, “Shape memory particles for biomedical uses,” Patent application (WO2016164458A1) filed on April 6, 2016.
2. A. Kumar, D. Lough, C. Madsen, and Q. Guo, “Bone healing, angiogenesis-promoting and vasculogenesis-producing system,” Patent application (WO2016172004) filed on April 15, 2016.
3. J.H. Elisseeff, Q. Guo, and S. Majumdar, “Compositions comprising cyclodextrin incorporated collagen matrices for use in biomedical applications,” Patent application (US20170043021A1) filed on September 10, 2015.
4. J.H. Elisseeff, Q. Guo, S. Majumdar, and A. Singh, “Cornea mimetic biomaterials: vitrified collagen-cyclodextrin implants,” Patent Application (WO2016171745A1) filed on April 24, 2015.
5. M.M. Trexler, J.H. Elisseeff, D.G. Mulreany, Q. Guo, J.L. Breidenich, J.P. Maranchi, J.L. Graham, J.B. Patrone, M.W. Patchan, and X. Calderon-Colon, “Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof,” Approved by USPTO on April 19, 2016. Patent #US9314531B2.