Faculty
Lab website: http://wulab.bme.sustech.edu.cn/
Education
2005-2008 Ph. D. in Chemistry, Clemson University
2001-2004 Ph. D. in Physics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, China
1998-2001 M. S. in Material Science, Jilin University, China
1994-1998 B. S. in Material Science, Qilu University of Technology, China
Work Experience
2016-now Professor of Biomedical Engineering, Southern University of Science and Technology
2012-2016 Professor of Biomedical Engineering College of Electronic Science and Engineering, Jilin University
2008-2012 Postdoctoral Fellow, Department of Chemistry, University of Washington
2004-2005 Postdoctoral Fellow, Department of Physics, Clemson University
Research Interests
Multifunctional probes for biomedical diagnostics and therapeutics
Fluorescent semiconductor polymer dots for biological imaging and sensing
Single molecule techniques for biomolecular dynamics and cellular processes
Photophysics of semiconducting polymers and lanthanide materials
Design/construction of spectroscopic and imaging instrumentation
Honors and Awards
2012 Outstanding Young Scholars of National Science Foundation of China
2008 Outstanding Graduate Researcher Award, Department of Chemistry, Clemson University
2007 Departmental Research Incentive Award, Department of Chemistry, Clemson University
2003 Da-Heng Optical Research Award, Chinese Academy of Sciences
Selected Publications
1. Mi, F.; Liu, Z.; Wang, X.; Wang, Y.; Yang, J.; Wang, Z.; Yin, S.; Fang, X.; Shu, P.*; Zhang, X.*; Wu, C.*, Deep Red Light Driven Hydrogen Evolution by Heterojunction Polymer Dots for Diabetic Wound Healing. Angewandte Chemie International Edition, 2024, 63(29), e202402133.
2. Li, D.; Shi, T.; Xiao, Y.; Wu C.*, Sensorless Adaptive Optics in the Second Near-Infrared Window for Deep Vascular Imaging In Vivo. Optics Letters, 2024, 49(14), 4002-4005.
3. Chen, D.; Qi, W.; Liu, Y.; Yang, Y.; Shi, T.; Wang, Y.; Fang, X.; Wang, Y.; Xi, L.*; Wu, C.*, Near-Infrared II Semiconducting Polymer Dots: Chain Packing Modulation and High-Contrast Vascular Imaging in Deep Tissues. ACS Nano, 2023, 17 (17), 17082-17094.
4. Liu, J.; Liu, Z.; Mi, F.; Yao, Z.; Fang, X.; Wang, Y.; Zhao, Z.*; Wu, C.*, Fluorescence Lifetime Multiplex Imaging in Expansion Microscopy with Tunable Donor–Acceptor Polymer Dots. Chemical & Biomedical Imaging, 2023, 1 (6), 550–557.
5. Wang, C.; Sun, Y.; Huang, S.; Wei, Z.; Tan, J.; Wu, C.*; Chen, Q.*; Zhang X.*, Self-Immolative Photosensitizers for Self-Reported Cancer Phototheranostics. Journal of the American Chemical Society, 2023, 145(24), 13099-13113.
6. Zhang, Z.; Li, W.; Liu, Y.; Fang, X.; Wu, C.*, Semiconducting Polymer Nanoparticles in the Second Near-Infrared Region for Biomedical Imaging and Therapy. Advanced Optical Materials, 2023, 11(11), 2202052.
7. Liu, S.; Liu, Y.; Zhang, Z.; Wang, X.; Yang, Y.; Sun, K.; Yu, J.; Chiu, D.T.; Wu, C.*, Near-Infrared Optical Transducer for Dynamic Imaging of Cerebrospinal Fluid Glucose in Brain Tumor. Analytical Chemistry, 2022, 94, 14265–14272.
8. Liu, J.; Fang, X.; Zhang, Z.; Liu, Z.; Liu, J.; Sun, K.; Yuan, Z.; Yu, J.; Chiu, D.T.; Wu, C.*, Long-Term In Vivo Glucose Monitoring by Polymer-Dot Transducer in an Injectable Hydrogel Implant. Analytical Chemistry, 2022, 94(4), 2195–2203.
9. Ao, J.; Fang, X.; Mao, X.; Ling, J.; Kang, H.; Park, S.; Wu, C.*, Ji, M.*, Switchable Stimulated Raman Scattering Microscopy with Photochromic Vibrational Probes. Nature Communications, 2021, 12(1), 3089.
10. Liu, J.; Fang, X.; Liu, Z.; Li, R.; Yang, Y.; Sun, Y.; Zhao, Z.; Wu, C.*, Expansion Microscopy with Multifunctional Polymer Dots. Advanced Materials, 2021,33(25), 2007854.
11. Chen, D.; Liu, Y.; Zhang, Z.; Liu, Z.; Fang, X.; He, S.; Wu, C.*, NIR-II Fluorescence Imaging Reveals Bone Marrow Retention of Small Polymer Nanoparticles. Nano Letters, 2021, 21(1) :798–805
12. Liu, Y.; Liu, J.; Chen, D.; Wang, X.; Zhang, Z.; Yang, Y.; Jiang, L.; Qi, W.; Ye, Z.; He, S.; Liu, Q.; Xi, L.; Zou, Y.*; Wu, C.*, Fluorination Enhances NIR‐II Fluorescence of Polymer Dots for Quantitative Brain Tumor Imaging. Angewandte Chemie International Edition, 2020, 59 (47): 21049-21057.
13. Chen, H.; Wang, F.; Liu, M.; Qian, M.; Men, X.; Yao, C.; Xi, L.; Qin, W.; Qin, G.*; Wu, C.*, Near-Infrared Broadband Polymer-Dot Modulator with High Optical Nonlinearity for Ultrafast Pulsed Lasers. Laser & Photonics Reviews, 2019, 13(2), 1800326.
14. Sun, K.; Yang, Y.; Zhou, H.; Yin, S.; Qin, W.; Yu, J.; Chiu, D.T.; Yuan, Z.; Zhang, X.; Wu, C.*, Ultrabright Polymer-Dot Transducer Enabled Wireless Glucose Monitoring via a Smartphone. ACS Nano, 2018, 12 (6), 5176–5184
15. Chang, K.; Liu, Z.; Fang, X.; Chen, H.; Men, X.; Yuan, Y.; Sun, K.; Zhang, X.; Yuan, Z.; Wu, C.*, Enhanced Phototherapy by Nanoparticle-Enzyme via Generation and Photolysis of Hydrogen Peroxide. Nano Letters, 2017, 17 (7), 4323-4329.
16. Wu, C.; Chiu, D. T., Highly Fluorescent Semiconducting Polymer Dots for Biology and Medicine. Angewandte Chemie International Edition, 2013, 52 (11), 3086-3109.
17. Wu, C.; Hansen, S. J.; Hou, Q.; Yu, J.; Zeigler, M.; Jin, Y.; Burnham, D. R.; McNeill, J. D.; Olson, J. M.; Chiu, D. T., Design of Highly Emissive Polymer Dot Bioconjugates for In Vivo Tumor Targeting. Angewandte Chemie International Edition, 2011, 50 (15), 3430-3434.
18. Wu, C.; Schneider, T.; Zeigler, M.; Yu, J.; Schiro, P. G.; Burnham, D. R.; McNeill, J. D.; Chiu, D. T., Bioconjugation of Ultrabright Semiconducting Polymer Dots for Specific Cellular Targeting. Journal of American Chemical Society, 2010, 132 (43), 15410-15417.
19. Wu, C.; Jin, Y.; Schneider, T.; Burnham, D. R.; Smith, P. B.; Chiu, D. T., Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry. Angewandte Chemie International Edition, 2010, 49 (49), 9436-9440.
20. Wu, C.; Bull, B.; Christensen, K.; McNeill, J., Ratiometric Single‐Nanoparticle Oxygen Sensors for Biological Imaging. Angewandte Chemie International Edition, 2009, 48 (15), 2741-2745.
21. Wu, C.; Zheng, Y.; Szymanski, C.; McNeill, J., Energy Ttransfer in a Nanoscale Multichromophoric System: Fluorescent Dye-Doped Conjugated Polymer Nanoparticles. Journal of Physical Chemistry C, 2008, 112(6), 1772-1781.
22. Wu, C.; Bull, B.; Szymanski, C.; Christensen, K.; McNeill, J., Multicolor Conjugated Polymer Dots for Biological Fluorescence Imaging. ACS Nano, 2008, 2 (11), 2415-2423.
23. Wu, C.; Szymanski, C.; Cain, Z.; McNeill, J., Conjugated Polymer Dots for Multiphoton Fluorescence Imaging. Journal of American Chemical Society, 2007, 129 (43), 12904-12905.
24. Wu, C.; Peng, H.; Jiang, Y.; McNeill, J., Energy Transfer Mediated Fluorescence from Blended Conjugated Polymer Nanoparticles. Journal of Physical Chemistry B, 2006, 110(29), 14148-14154.
25. Wu, C.; Szymanski, C.; McNeill, J., Preparation and Encapsulation of Highly Fluorescent Conjugated Polymer Nanoparticles. Langmuir, 2006, 22(7), 2956-2960.