Self-introduction:
Wenqin Lu, Research Assistant Professor at Southern University of Science and Technology. Graduated with a bachelor's degree from Northwest A&F University in 2015, and obtained a doctoral degree from the same university in 2020. Joined the research group of Professor Jixian Zhai in the Department of Biology at Southern University of Science and Technology in 2021, engaging in postdoctoral research and working till present. Primarily involved in research areas including the study of mRNA poly(A) tail length regulation using long-read sequencing technology and the development of high-throughput single-cell multi-omics techniques. In recent years, has published multiple high-impact research papers as a first or co-author in journals such as Nature Plants, The Plant Cell, Molecular Plant, Molecular Plant Pathology, and others.
Research Interests：
◆Investigation of the poly(A) tail length regulation mechanism in plants;
◆Development of high-throughput single-cell multi-omics methods.
Professional Experience：
◆Since 2023, Research Assistant Professor, Southern University of Science and Technology;
◆2021-2023, Postdoctoral Fellow, Southern University of Science and Technology;
Educational Background：
◆2015-2020, PhD, College of Plant Protection, Northwest A&F University.
◆2011-2015, BS, College of Innovation and Experiment, Northwest A&F University.
Selected Publication：
1. Jia J.#, Lu W. #, Lui B., Fang H., Yu Y., Mo W., Zhang H., Jin X., Shu Y., Long Y., Pei Y., and Zhai J.* (2022) An atlas of plant full-length RNA reveals tissue-specific and monocots-dicots conserved regulation of poly(A) tail length. Nature Plants. 8: 1118-1126.
2. Lu W. and Zhai J. (2022) An atlas of plant poly(A) tail length reveals phased peaks and tissue-specific patterns. Nature Plants. 8: 994–995
3. Lu W.#, Deng F.#, Jia J., Chen X., Li J., Wen Q., Li T., Meng Y., and Shan W.* (2020) The Arabidopsis AtERF019 gene negatively regulates plant resistance to Phytophthora parasitica by suppressing PAMP-triggered immunity. Molecular Plant Pathology. 21: 1179-1193.
4. Wang R., Zhou, R., Meng Y., Zheng J., Lu W., Yang Y., Yang J., Wu Y.*, and Shan W.* (2023). Specific detection of Phytophthora parasitica by recombinase polymerase amplification (RPA) assays based on a unique multi-copy genomic sequence. Plant Disease. doi:10.1094/PDIS-04-23-0722-RE.
5. Yang Y., Zhao Y., Zhang Y., Niu L., Li W., Lu W., Li J., Schafer P., Meng Y., and Shan W.* (2022). A mitochondrial RNA processing protein mediates plant immunity to a broad spectrum of pathogens by modulating the mitochondrial oxidative burst. Plant Cell, 34(6): 2343-2363.
6. Gou X., Zhong C., Zhang P., Mi L., Li Y., Lu W., Zheng J., Xu J., Meng Y., and Shan W.* (2022). miR398b and AtC2GnT form a negative feedback loop to regulate Arabidopsis thaliana resistance against Phytophthora parasitica. Plant Journal.111(2):360-373.
7. Wen Q., Sun M., Kong X., Yang Y., Zhang Q., Huang G., Lu W., Li W., Meng Y., and Shan W.* (2021). The novel peptide NbPPI1 identified from Nicotiana benthamiana triggers immune responses and enhances resistance against Phytophthora pathogens. Journal of Integrative Plant Biology. 63(5): 961-976.
8. Fan G., Yang Y., Li T., Lu W., Du Y., Qiang X., Wen Q., and Shan W.* (2018) A Phytophthora capsici RXLR effector targets and inhibits a plant PPIase to suppress endoplasmic reticulum-mediated immunity. Molecular Plant. 11: 1067-1083.
9. Jia J., Lu W., Zhong C., Zhou R., Xu J., Liu W., Gou X., Wang Q., Yin J., Xu C. and Shan W.* (2017). The 25–26 nt small RNAs in Phytophthora parasitica are associated with efficient silencing of homologous endogenous genes. Frontiers in Microbiology. 8: 773.
(# co-first author, *corresponding author)
